Main Organiser

Julius Centre University of Malaya

Co-organiser

Department of Social and Preventive Medicine, Faculty of Medicine, University of Malay

Supported by

University of Malaya

ASSOCIATION OF HYPERTRIGLYCERIDEMIC WAIST WITH CARDIOMETABOLIC RISK FACTORS AMONG A MULTI-ETHNIC WORK COHORT IN MALAYSIA

Author

Moy FM, Awang Bulgiba

Institution

Julius Centre University of Malaya, Department of Social & Preventive Medicine, Faculty of Medicine, University of Malaya

Abstract

Objectives: To study the association of hypertriglyceridemic waist (HTGW) with cardiometabolic risk factors in a multi-ethnic work cohort in Malaysia.

Methods: This was a cross sectional study. A total of 1923 employees (aged 35-60 years) of a public university in Kuala Lumpur participated in this study. There were slightly more females (53%) and majority were of Malay ethnicity (78%), followed by Chinese (8.4%), Indian (10%) and others. Anthropometric measurements, blood pressure, fasting blood glucose, lipid profile, uric acid were measured. HTGW was diagnosed using anthropometric criteria for the Asian population (waist circumference: for men, greater than or equal to 90 cm; for women, greater than or equal to 80 cm) and fasting plasma triglycerides (TGs) greater than or equal to 1.70 mmol/l (greater than or equal to150 mg per 100 ml).

Results: The prevalence of HTGW was 25.2% (men: 32.7%, women: 18.6%) and was significantly more predominant among Malays and Indians (P=0.003). HTGW was not associated with age nor occupational status in our cohort. Males had the odds of 1.9 (95%CI: 1.4-2.5) for HTGW. After adjusting for all confounders, participants with HTGW had higher odds of having higher levels of total cholesterol (OR: 4.3, 2.7-6.9), fasting blood glucose (1.7, 1.3-2.3) and uric acid (1.5, 1.1-1.9), lower levels of high-density lipoprotein-cholesterol (2.6, 2.0-3.3) and a greater degree of obesity (overweight : 4.4, 2.6-7.4 obese: 7.4, 4.4-12.6).

Conclusion: HTGW is prevalent in our work cohort. Individuals with HTGW are predisposed to cardiometabolic risks. HTGW may be an alternative to detect population at risk for Metabolic Syndrome.