Main Organiser

Julius Centre University of Malaya

Co-organiser

Department of Social and Preventive Medicine, Faculty of Medicine, University of Malay

Supported by

University of Malaya

COEXISTING FACTORS AND COMPLICATIONS FOLLOWING ISOLATED CABG IN DIABETIC PATIENTS

Author

Huq, Molla

Institution

Monash University

Abstract

Objectives: To identify prominent pre-operative and intra-operative factors and post-operative complications for diabetic patients underwent isolated coronary artery bypass grafting (CABG) in Australia.

Methods: Isolated CABG in diabetics between 2001 and 2010 in Australia was used. Data was analyzed using simple and multiple logistic regression, Kruskal-Wallis test and Kaplan Meier survival method. A p-value of < 0.05 was considered as significant.

Results: 6932 of 21271 isolated CABG were diabetics. Diabetics were more likely to have poorer renal function (OR 2.3, 95% CI 1.8-2.9), ejection fraction (OR 1.4, 95% CI 1.3-1.5), higher peripheral vascular disease (OR 1.9, CI 1.7-2.0) and cerebrovascular disease (OR 1.4, 95% CI 1.3-1.4) and be overweight (OR 1.6, 95% CI 1.5-1.7). Diabetics were received more distal anastomoses and non-arterial grafts, more likely to require red blood cells transfusion (OR 1.4, 95% CI 1.3-1.5), readmission to ICU (OR 1.6, 95% CI 1.3-1.8) and re- intubation (OR 1.6, 1.4-2.0). Diabetics were more likely to develop post-operative complications including renal failure, deep sternal wound infection and septicaemia. Return to theatre and readmission among diabetics were higher. Mortality among diabetics was also higher (OR 1.4, 95% CI 1.2-1.7).

Conclusion: Pre-operative and intra-operative risk factors and post-operative complications in the diabetic population having isolated CABG have been analyzed. This will lead to a better understanding of the management of diabetic patients undergoing isolated CABG