Main Organiser

Julius Centre University of Malaya

Co-organiser

Department of Social and Preventive Medicine, Faculty of Medicine, University of Malay

Supported by

University of Malaya

EARLY POSTOPERATIVE HEMODYNAMICS AND CLINICAL OUTCOMES OF PATIENTS RECEIVING FREEDOM SOLO AORTIC VALVE REPLACEMENT IN UMMC

Author

Hasrina H

Institution

Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia

Abstract

Objectives: FS is a stentless aortic valve bioprosthesis that use a single running suture line implanted in supra-annular position. Current study aims to assess the early postoperative hemodynamics and clinical outcomes of patients receiving FS AVR.

Methods: 4 patients (2 male; 2 female; mean age 49.25 ± 23.78 years; range: from 25 to 73) who underwent AVR with FS valve in a single center were enrolled in the study. 2 patients underwent AVR for aortic stenosis and others for aortic regurgitation. Clinical and biological outcomes were recorded. Echocardiographic parameters were compared between preoperative and within 5 months postoperatively

Results: There was no early mortality reported. Late death was reported once which was non valve related. There were 2 patients developed early postoperative complication but it was not attributed to the valve itself. The mean transvalvular pressure gradient was 26.50 ± 11.90 mmHg preoperatively and 15.25 ± 10.11 mmHg postoperatively. The mean AVA for patients having stenosis improved from 0.74 ± 0.23 cm2 preoperatively to 1.50 ± 0.57 cm2 postoperatively. Preoperatively, the mean LVEF was 65.75 ± 6.29 % and postoperatively 61.25±11.84 %. The mean cross-clamp time (CCT) for isolated valve replacement was 80.5 ± 21.92 minutes and 147.00 ± 26.87 minutes with concomitant procedures. The mean lowest postoperative platelet count recorded was 24.50 ± 6.19 (x109/L). The mean platelet count at discharge was 128.75 ±10.11 (x109/L)

Conclusion: The result demonstrated good short- term clinical and hemodynamic outcomes in patients underwent FS aortic valve replacement. However, the study also showed severe thrombocytopenia after FS valve implantation