Main Organiser

Julius Centre University of Malaya

Co-organiser

Department of Social and Preventive Medicine, Faculty of Medicine, University of Malay

Supported by

University of Malaya

EVALUATION OF CARDIAC AND OTHER CLINICAL MALFORMATIONS OF CLEFT PALATE PATIENTS IN SRI LANKA

Author

Prabodha L B L

Institution

Faculty of Medicine, University of Ruhuna, Sri Lanka.

Abstract

Objectives: Cleft palate is one of the commonest congenital malformations with a worldwide prevalence of 0.43 to 2.45 per 1000. It is a multifactorial genetic disorder that involves both genetic and environmental factors. The objective of this study was to identify the cardiac anomalies and other clinical manifestations in patients with cleft palate in Sri Lanka.

Methods: Patients with cleft palate were identified at Oro-Maxillo-Facial Unit, Teaching Hospital Karapitiya, Galle, Sri Lanka, and relevant data were obtained from case notes, interviews and examination of the patient.

Results: There were 162 cleft palate patients of whom 59% were females. The age of the subjects ranged from 2 weeks to 49 years of which 83.3% were below 12 years. The cleft was limited to the soft palate in 125 patients. A total of ninety one subjects (56.2%) had other associated clinical manifestations. There were fifteen (9.3%) subjects with congenital heart defects including eight subjects with Atrial Septal Defects (ASD), three subjects with Ventricular Septal Defects (VSD) and one subject with the Tetralogy of Fallot (TOF).

Conclusion: The finding of this study confirms the association of cardiac and other clinical manifestations and need of genetic evaluation of patients with cleft palate.