Main Organiser

Julius Centre University of Malaya

Co-organiser

Department of Social and Preventive Medicine, Faculty of Medicine, University of Malay

Supported by

University of Malaya

A RANDOMISED CONTROLLED TRIAL OF THREE LAYER TUBULAR COMPRESSION SYSTEM FOR VENOUS LEG ULCERS

Author

Weller CD, Evans S, Staples M, McNeil JJ

Institution

Monash University

Abstract

Objectives: To compare three layer tubular bandage system (3L) with short stretch compression bandage (SS) for treatment of venous leg ulcers (VLU). Multi-component compression is best practice treatment for venous leg ulcers, but many compression systems are not well tolerated and are unaffordable. The safety and efficacy of 3L has not been evaluated in a randomized controlled trial (RCT) despite use in clinical settings.

Methods: Multicentre RCT recruited 46 participants with VLU from wound clinics in Victoria and Queensland, Australia. Outcome measures included percentage wound reduction from baseline compared to week 12 following randomization, proportion of ulcers healed, Quality of Life measures, self-reported bandage adherence, recurrence rates and cost effectiveness.

Results: Proportion of healed ulcers was higher for 3L group [17/23 (74%) vs. 10/22 (46%) (p=0.05)]. Mean ulcer percentage reduction for 3L group was 82.4% vs.70.1% Self-reported compliance and study-related adverse events were similar in both groups. Health-related quality of life scores improved but differences between groups were not significant. Cost per ulcer healed in 3L was A$200 vs. A$618 in SS (p = 0.0001).

Conclusion: The 3L tubular compression system applied weekly for up to 12 weeks increased healing rates was well tolerated and more cost effective when compared to SS bandage.