Main Organiser

Julius Centre University of Malaya

Co-organiser

Department of Social and Preventive Medicine, Faculty of Medicine, University of Malay

Supported by

University of Malaya

PREDICTORS OF FUTURE 3 ANTIHYPERTENSIVE MEDICATION USE IN PATIENTS WITH ELEVATED BLOOD PRESSURE

Author

Ching Siew Mooi

Institution

Universiti Putra Malaysia

Abstract

Objectives: This study examines the predictors of future 3 antihypertensive medication uses over a 10-year period.

Methods: Data was obtained from the 10-year retrospective cohort of 1547 randomly selected adult patients registered with the Department of Primary Care Medicine Clinic at the University of Malaya Medical Centre. Demographic data, blood pressure (BP) and anti-hypertensive drug usage in 1998, 2002 and 2007 were captured from the patients’ record.

Results: Mean age was 56.5 years (SD±10.0); 35% was male. The mean systolic blood pressure (SBP) and diastolic BP were 145.8 ±18.2mmHg and 87.5± 10 mmHg respectively. In 1998 and 2007, 57.7% and 78.4% were on antihypertensive drug treatment. At entry, only 13 (1.5%) of participants were put on 3 antihypertensive medication. After 10 years, the percentage of 3 antihypertensive agents’ usage was increased to 222 (19.8%). Blood pressure controls among these groups were 15.4% and 37.4% in 1998 and 2007 respectively. Analysis of logistic regression was performed. The independent baseline predictors of future 3 antihypertensive medication uses include SBP and weight (OR 1.022, 95% CI 1.013-1.031) and (OR1.019, 95% CI 1.007-1.032).

Conclusion: Usage of 3 antihypertensive over a 10- year period is high. Every effort should be made to achieve target blood pressure.