Main Organiser

Julius Centre University of Malaya

Co-organiser

Department of Social and Preventive Medicine, Faculty of Medicine, University of Malay

Supported by

University of Malaya

COLORECTAL CANCER IN ULCERATIVE COLITIS IN TAIWAN: A NATIONWIDE POPULATION BASED STUDY

Author

C.Y. Chen, Y.B. Huang, T.C. Lee

Institution

Kaohsiung Medical University

Abstract

Objectives: A rising trend of ulcerative colitis (UC)- associated colorectal cancer (CRC) has been observed and a numbers of meta-analysis and systemic review have indicated ulcerative colitis have high risk to cause colorectal cancer. We conducted this study to investigate the risk of ulcerative colitis-associated colorectal cancer in Taiwan.

Methods: This is a retrospective population database research which was identified UC cases from Nation Health Insurance Research Database (NHIRD), 1998-2008.

Results: A total of 71 colorectal cancers were observed in patients with UC. The overall prevalence of ulcerative colitis-associated colorectal cancer was 4.7%. The average age at diagnosis CRC in UC patients were 52.8 years. Moreover, the mean duration of UC before the development of CRC was 23.4 months.

Conclusion: The clinical epidemiology of colorectal cancer with UC patients was similar with other countries. The UC-associated CRC may be increasing in our country and other Asian countries. Continued vigilance in follow-up for UC- associated CRC in Taiwan and Asia is recommended.