Main Organiser

Julius Centre University of Malaya

Co-organiser

Department of Social and Preventive Medicine, Faculty of Medicine, University of Malay

Supported by

University of Malaya

ASSESSING THE RISK OF ERECTILE DYSFUNCTION IN PATIENTS RECEIVING METHADONE MAINTENANCE THERAPY (MMT)

Author

N.J. Nik Ruzyanei, M. Noormazita, S. Abdul Aziz,B. Azlin, I. Normala, S. Hatta.

Institution

Universiti Kebangsaan Malaysia

Abstract

Objectives: Erectile dysfunction (ED) is a known side effect of methadone. Its occurrence may interfere with the treatment adherence and benefits. This study aimed to determine the rate of ED and its predictive factors in male patients on methadone maintenance therapy (MMT) in a Malaysian sample.

Methods: A total of 108 participants with heroin dependence diagnosed using the Structured Clinical Interview for DSM-IV Axis-I Disorder (SCID- I) on MMT completed the International Index of Erectile Function-15(IIEF-15), Beck Depression Inventory (BDI), socio-demography and other clinical variables.

Results: The ED rate among men on MMT was 68.5% (mild ED=36.1 %, mild to moderate=22.2% and severe ED=3.7%). Older age (p=0.002), concurrent illicit heroin use (p=0.024) and older partners(p=0.039) were significantly associated with ED. The methadone dose and duration of methadone treatment were not significantly associated with ED. Multivariate analysis showed that older age remains the only significant predictor of ED with (adjOR=1.07, CI=1.02-1.16).

Conclusion: ED was highly prevalent; that compels routine assessment of sexual function in patients on methadone. It is reassuring that current clinical practice of MMT in Malaysia showed no significant association with ED. This helps clinicians to treat opiate dependents with confidence and allay anxiety among the potential clients.